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Organic Acids and Nutritional Testing

Organic acids are metabolic  bi-products that are produced in the body's production of  energy, detoxification, neurotransmitter conversion and breakdown, or intestinal microbial activity. Elevation of specific organic acids detected in urine often indicates a metabolic block or inhibition. The metabolic block may be due to a nutrient deficiency, an  enzyme deficit, toxic build-up or effect of drugs. Also there are also biomarkers of intestinal bacterial or yeast overgrowth.

The Organix Comprehensive nutritional test by Genova Diagnostics profile provides valuable information from a simple urine specimen. This organic acids nutritional test is very helpful for determining:

  • Functional vitamin and mineral status
  • Amino acid deficiencies such as carnitine and NAC
  • Oxidative damage and antioxidant need
  • Phase I & Phase II detoxification function
  • Functional B-complex vitamin need
  • Neurotransmitter status
  • Mitochondrial energy production
  • Methylation capability
  • Lipoic acid and CoQ10 status
  •  bacterial and yeast overgrowth

  • 2-Methylhippurate
  • 3,4 Dihydroxyphenylpropionate
  • 5-hydroxyindoleacetate
  • 8-Hydroxy-2'-deoxyguanosine*

  • Adipate
  • Alpha-Hydroxybutyrate
  • Alpha-Keto-Beta-Methylvalerate
  • Alpha-Ketoglutarate
  • Alpha-Ketoisocaproate
  • Alpha-Ketoisovalerate
  • Benzoate
  • Beta-Hydroxybutyrate
  • Beta-Hydroxyisovalerate
  • Citrate
  • Creatinine
  • D-Arabinitol*
  • D-Lactate*
  • Ethylmalonate
  • Formiminoglutamate
  • Fumarate
  • Glucarate
  • Hippurate
  • Homvanillate
  • Hydroxymethylglutarate
  • Indican
  • Isocitrate
  • Kynurenate
  • L-Lactate*
  • Malate
  • Methylmalonate
  • Orotate
  • Phenylacetate
  • Phenylpropionate
  • Picolinate*
  • Pyroglutamate
  • Pyruvate
  • Quinolinate
  • Suberate
  • Succinate
  • Sulfate
  • Tricarballylate
  • Vanilmandelate
  • Xanthurenate
  • cis-Aconitate
  • p-Hydroxybenzoate
  • p-Hydroxyphenylacetate
  • p-Hydroxyphenyllactate